Organonitrogen Compounds
Medchemexpress LLC BAFF/TNFSF13B Trimer 50ug | 50ug
BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA forming a key ligand-receptor pathway together with TNFSF13/APRIL These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity BAFF/TNFSF13B Trimer Protein Human (HEK293 His-Flag) is the recombinant human-derived BAFF/TNFSF13B protein expressed by HEK293 with N-His N-Flag labeled tag
eMolecules 75390-44-2 | Ambeed | 4-Phenylthiazole-2-carbaldehyde | 100mg | 595927454 | A503314 | MFCD02665589 | 189.23 | C10H7NOS
Ambeed | 4-Phenylthiazole-2-carbaldehyde | 100mg | 595927454 | A503314 | 75390-44-2 | MFCD02665589 | 189.230 | C10H7NOS
Medchemexpress LLC Ask1-in-2 | 2541792-70-3 | 99.6% | 364.38 g·mol⁻¹ | C19H17FN6O | 5 MG
ASK1-IN-2 is a small-molecule, orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 32.8 nM. It is supplied as a white to off-white solid and is available in multiple package sizes and as DMSO solutions for research use; preclinical studies report activity in dextran sulfate sodium (DSS)-induced ulcerative colitis models.
- Potent ASK1 inhibition (IC50 32.8 nM).
- Orally active compound demonstrated in preclinical models.
- Shown to improve DSS-induced ulcerative colitis in mice.
- Blocks ASK1-p38/JNK signaling and reduces inflammatory cytokines.
- High purity (99.6%) and solid, white to off-white physical form.
- Available as solid, solid + solvent, and solution formats for flexible use.
- Powder storage: -20°C for long-term stability; solvent storage guidelines provided.
Medchemexpress LLC L-Carnitine hydrochloride | 6645-46-1 | 99.9% | 10 MM * 1 ML
L-Carnitine hydrochloride is a highly polar, small zwitterion that functions as an essential co-factor for the mitochondrial β-oxidation pathway. It transports long-chain fatty acyl-CoAs into the mitochondria for degradation and acts as an antioxidant, ameliorating metabolic imbalances.
- Essential co-factor for mitochondrial β-oxidation
- Transports long-chain fatty acyl-CoAs for degradation
- Functions as an antioxidant
- Ameliorates metabolic imbalances
Sigma Aldrich Fine Chemicals Biosciences N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride BioXtra | 25952-53-8 | MFCD00012503 | 10G
N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride BioXtra | Mol Wt: 191.7 | 25952-53-8 | MFCD00012503 | 10G
Sigma Aldrich Fine Chemicals Biosciences Histamine dihydrochloride >=99% (TLC), powder | 56-92-8 | MFCD00012703 | 10MG
Histamine dihydrochloride >=99% (TLC), powder | Purity: >=99% (TLC) | Mol Wt: 184.07 | 56-92-8 | MFCD00012703 | 10MG
Sigma Aldrich Fine Chemicals Biosciences BIS-TRIS anhydrous, free-flowing, Redi-Dri(TM), >=98.0% | 6976-37-0 | MFCD00002853 | 1KG
BIS-TRIS anhydrous, free-flowing, Redi-Dri(TM), >=98.0% | Purity: >=98.0% | Mol Wt: 209.24 | 6976-37-0 | MFCD00002853 | 1KG
Selleck Chemical LLC RMC-6291-E1606-25MG
RMC-6291 is an orally active and covalent inhibitor of KRASG12C(ON) RMC-6291 forms a tri-complex within tumor cells between KRASG12C(ON) and cyclophilin A (CypA)
Sigma Aldrich Fine Chemicals Biosciences 4,4',4''-Tris[phenyl(m-tolyl)amino]triphenylamine 98.0% | 124729-98-2 | MFCD00799401 | 5G
4,4',4''-Tris[phenyl(m-tolyl)amino]triphenylamine 98.0% | Purity: 98.0% | Mol Wt: 789.02 | 124729-98-2 | MFCD00799401 | 5G
Medchemexpress LLC DNA antisense oligonucleotide (Tofersen) with 2'-O-(2-methoxyethyl) modifications | 2088232-70-4 | 95.5% | 7128.00 | C230H317N72O123P19S15 | 5 MG
Tofersen is an antisense oligonucleotide that reduces synthesis of superoxide dismutase 1 (SOD1) protein via RNase H-dependent degradation of SOD1 mRNA. It is supplied as a purified, sequence-modified oligonucleotide for laboratory research, primarily in studies related to amyotrophic lateral sclerosis (ALS).
- Antisense mechanism mediating RNase H-dependent degradation of SOD1 mRNA.
- Suitable for ALS-related research applications.
- Provided as a purified oligonucleotide with documented purity and molecular weight.
- Sequence modified with 2'-O-(2-methoxyethyl) groups for increased stability.
- Available in small-mass quantities appropriate for experimental use.
- Certificate of analysis available for batch verification.
Medchemexpress LLC N-hexanoyl-L-homoserine lactone | 147852-83-3 | MFCD12912260 | 98.8% | 199.25 g/mol | C10H17NO3 | 5 MG
N-hexanoyl-L-homoserine lactone is a short-chain acyl-homoserine lactone used as a bacterial quorum-sensing signaling molecule and as an analytical standard for microbiology and biochemical research. Provided as a purified standard, it is suitable for assay development, calibration, and mechanistic studies.
- Used as a quorum-sensing standard in bacterial signaling and biofilm research.
- High purity (98.8%) for analytical and research applications.
- Molecular formula C10H17NO3; molecular weight 199.25 g/mol.
- Available in small solid quantities and preprepared DMSO solutions for convenience.
- Certificate of analysis provided for lot traceability.
- Soluble in common organic solvents such as DMSO.
Apexbio Technology LLC MYK-461 1642288-47-8 25mg
MYK-461 is a small-molecule inhibitor interacting directly with cardiac myosin heavy chain to modulate myocardial contraction It specifically reduces myocardial contractility through inhibition of cardiac myosin ATPase enzymatic activity thereby limiting myosin-mediated phosphate release without affecting ADP dissociation rates In rodent cardiomyocytes MYK-461 demonstrates dose-dependent reductions in fractional shortening and sarcomeric force generation without impacting calcium transient dynamics Its inhibitory potency against cardiac myosin ATPase surpasses that observed for skeletal muscle isoforms In preclinical hypertrophic cardiomyopathy mouse models MYK-461 administration attenuates cardiac contractile function facilitating investigations into myocardial contractility regulation and potential therapeutic strategies against hypertrophic cardiomyopathy